mechanisms and pathways of heterotrimeric g protein

Bacterial Responses to PH - No. 221

ISBN: , SKU: , AUTHOR: Chadwick, Derek / Cardew, Gail / Gardew, Gail, PUBLISHER: John Wiley & Sons, Microbial responses to acidic and alkaline pH are important in many areas of bacteriology. For example, the mechanisms of resistance to acidic pH are important in the understanding of the passage of human pathogens through the acid of the stomach; and an understanding of microbial degradation of alkaline industrial waste is important for the environment. Bringing together contributions from an international and interdisciplinary group of experts working on the many aspects of bacterial cellular responses to pH, this stimulating volume draws together new and innovative work in this area. It delineates both similarities and differences between mechanisms of tolerance and response, providing readers with an invaluable resource on the subject.

Enzyme Kinetics: In Focus

ISBN: , SKU: , AUTHOR: Cornish-Bowden, A. / Wharton, C. W. / Cornish-Bowden, Athel, PUBLISHER: Oxford University Press, USA, There is a core of enzyme kinetics that every biochemist needs to be familiar with, and every biochemistry student needs to be taught. This textbook presents that core in a logical and helpful manner and links traditional ideas on enzyme kinetics with the latest theories about enzyme mechanisms. It also discusses the possible implications of protein engineering. Students will find this book an invaluable aid in a notoriously difficult subject.

Molecular Biology of Parasitic Protozoa

ISBN: , SKU: , AUTHOR: Smith, Parsons / Smith, Deborah Ed. / Smith, Deborah F., PUBLISHER: Oxford University Press, USA, Protozoans are interesting creatures for several reasons, not least of which is their ability to live inside or among the cells of their host while resisting the host's cellular defences. The rigours of their lifestyle have resulted in the evolution of some remarkable adaptation at the biochemical level; many parasites have dispensed with entire metabolic pathways, and have evolved complex mechanisms for transmission to new hosts. Parasitic protozoa cause some of the major infectious diseases of humans and domestic animals. In recent years, new molecular biological techniques have opened up the study of the biology of these parasites, and tremendous advances have been made. This book covers this interesting and fast-moving field at an advanced level for which there is no other up-to-date book.

Molecular and Genetic Aspects of Nitrate Assimilation

ISBN: , SKU: , AUTHOR: Wray, John L. / Kinghorn, James R., PUBLISHER: Oxford University Press, USA, There is considerable interest in the mechanisms of nitrate regulation from both agriculture and industry because effective nitrate metabolism is vital for healthy plant growth. This book addresses aspects of both fungal and higher plant metabolism. It examines the genetics and molecular biology of nitrate uptake, reduction, and regulation, and identifies future research priorities.

Possible Mechanisms of the Neostriatum in Regulation of

ISBN: , SKU: , AUTHOR: N G Khrushchov T M Turpaev, PUBLISHER: Routledge, NA Acquista Ora

Negative Co-Receptors and Ligands

ISBN: , SKU: , AUTHOR: Ahmed, Rafi / Honjo, Tasuku, PUBLISHER: Springer, Adaptive immune responses serve as a key defense mechanism for the control of infections in vertebrates. Immune responses must be of sufficient strength to contain invading pathogens, antigen specific responses require regulatory mechanisms to ensure termination or downmodulation to avoid excessive damage to the host tissue. For both branches of the adaptive immune system, regulatory molecules i.e. coreceptors and ligands have been identified that control the signaling cascades initiated by engagement of the T cell and B cell antigen receptors. This book describes biological functions as well as molecular mechanisms of these molecules.

Interactive Biochemistry CD-ROM and Workbook

ISBN: , SKU: , AUTHOR: Grisham, Charles M. / Holt Rinehart & Winston, PUBLISHER: Thomson Brooks/Cole, This multimedia tool contains 16 modules, including Bioenergetic Calculations, Biomolecules, Amino Acids, Peptide Bonds, and Protein Structures, Sweet Isomers, Structures of Phospholipids, Nitrogenous Bases, and Nucleosides, Restriction Sites, Enzyme Kinetics and Mechanisms, metabolism and metabolic map Database, and Virtual Biochemical World. Icons integrated throughout Garrett and Grisham's, BIOCHEMISTRY, Second Edition and PRINCIPLES OF BIOCHEMISTRY: A HUMAN FOCUS, First Edition and Campbell's BIOCHEMISTRY, Third Edition prompt students to explore and engage in the activities and exercises provided on the INTERACTIVE BIOCHEMISTRY CD-ROM. Covering every major area of biochemistry, INTERACTIVE BIOCHEMISTRY CD-ROM features 120 Java Applets, 82 Chimea Tutorials, 8 Virtual Reality scenes, 600 Chimea structures of Intermediary Metabolites, and interactive problem-solving simulations. The CD-ROM and Workbook are designed to enhance classroom lectures as well as to assist students outside of the classroom. The workbook, which is packaged with the CD-ROM, guides students through the CD modules. Students are asked biochemical questions and they answer the questions in the workbook. The CD-ROM and workbook are value priced when packaged with the text.

Molecular Variability of Fungal Pathogens

ISBN: , SKU: , AUTHOR: Bridge, Paul Dennis / Clarkson, John / Couteaudier, Yvonne, PUBLISHER: CABI Publishing, This volume collects important current research on molecular variability in fungal pathogens. The first section reviews the major mechanisms involved. This is followed by a series of specific studies on variability in populations of different fungal pathogens. The book concludes with chapters on methods for interpreting such variability. The volume brings together research on a wide range of fungal pathogens, and case studies include pathogens of insects, nematodes, plants, and humans. Combining mechanisms, characterization, and interpretation across a wide range of applied mycology, this volume is a significant general text for those working on molecular characterization. Its broad spectrum of topics provides a multidisciplinary reference source within mycology, and the book will be suitable for postgraduate students and research scientists in applied mycology, including plant pathology, medical mycology and biological control.

Yugoslavia Unraveled: Sovereignty, Self-Determination,

ISBN: , SKU: , AUTHOR: Thomas, Raju G. C. / Thomas, Raju G. / Bardos, Gordon H., PUBLISHER: Lexington Books, Editor Raju G. C. Thomas and contributors examine underlying issues regarding the sources of religious nationalism and ethnic conflict, the territorial integrity and sovereignty of states, and the principle of self-determination and the right of secession from an existing state. Acquista Ora

Clinical Thrombosis

ISBN: , SKU: , AUTHOR: Kwaan, Hau C. / Samama, Meyer / O'Kelly, Charles J., PUBLISHER: CRC Press, State-of-the-art information on the topic of clinical thrombosis, including an introductory portion dealing with the principles of hemostasis and the pathogenesis of thrombosis, is presented in this text. The use of thrombolytic therapy in acute myocardial infarction is discussed. Other significant advances, such as the identification and understanding of the risk factors contributing to thrombosis such as Protein C and S deficiency, lupus anticoagulants, immune heparin-induced thrombocytopenia, new diagnostic techniques and newer modalities of therapy, are described. Clinical and pathophysiologic features of thrombosis disorders and special situations involving multiple organs are covered. This book also clarifies and updates the usefulness of the various diagnostic techniques.

Antibody Production

ISBN: , SKU: , AUTHOR: Glyn, Leonard Eleazar / Glynn, L. E. / Glynn, Leonard E., PUBLISHER: John Wiley & Sons, A practical guide to the production of antibodies. Describes the biosynthesis of antibody molecules by B lymphocytes and their progeny, the use of genetic markers in the elucidation of mechanisms of antibody synthesis, and of the generation of antibody diversity. Also deals with anomalies in antibody production which result in immunoglobulinopathies, involving qualitative or quantitative abnormalities, or both, in the immunoglobulins.

Immunology: A Short Course

ISBN: , SKU: , AUTHOR: Coico, Richard / Sunshine, Geoffrey, PUBLISHER: Wiley-Blackwell, "Immunology: A Short Course, Sixth Edition" introduces all the critical topics of modern immunology in clear and succinct yet comprehensive fashion. The authors offer a uniquely balanced coverage of classical and contemporary approaches, basic and clinical aspects. As with the previous editions, the strength of the text is in a complete review of modern immunology without burdening the reader with excessive data or theoretical discussions. Each chapter is divided into short, self-contained units that address key topics illustrated by uniformly drawn, full-color illustrations, many brand new to this edition. The sixth edition of this successful textbook newly covers: Toll-like receptors, their ligands and intracellular activation pathways The key role of activation induced cytidine deaminase (AID) in somatic hypermutation and class switch recombination. The autoimmune regulator ("AIRE)" gene in self-tolerance and autoimmunity T and B cell activation and the immunological synapse, as well as characterization and mechanisms of action of T regulatory cells Praise for the previous edition: "This book is clearly a precious resource for undergraduate, graduate and medical students alike... For those who need an introduction to the fascinating world of immunology, this book should most certainly spark the interest." "ANNALS OF BIOMEDICAL ENGINEERING"..". an excellent beginner's guide... the authors have done a terrific job of providing an overview of the field." "YALE JOURNAL OF BIOLOGY AND MEDICINE"

Computational Approaches to Morphology and Syntax

ISBN: , SKU: , AUTHOR: Roark, Brian / Sproat, Richard, PUBLISHER: Oxford University Press, USA, The book will appeal to scholars and advanced students of morphology, syntax, computational linguistics and natural language processing (NLP). It provides a critical and practical guide to computational techniques for handling morphological and syntactic phenomena, showing how these techniques have been used and modified in practice. The authors discuss the nature and uses of syntactic parsers and examine the problems and opportunities of parsing algorithms for finite-state, context-free and various context-sensitive grammars. They relate approaches for describing syntax and morphology to formal mechanisms and algorithms, and present well-motivated approaches for augmenting grammars with weights or probabilities.

Pathways to Cultural Awareness: Cultural Therapy with

ISBN: , SKU: , AUTHOR: Spindler, George D. / Spindler, George / Spindler, Louise, PUBLISHER: Corwin Press, Cultural therapy is a way of helping people cope with cultural diversity and societal inequity through the mediation of the school as a central institution for cultural transmission and maintenance. This book illustrates how cultural therapy can be applied in educational settings to promote better understanding among teachers and students. Each chapter presents a situation in which the author has been intimately involved, offering a variety of approaches to, and interpretations of, cultural therapy.

Oatley: Cities, Economic (P) Competition and Urban Policy

ISBN: , SKU: , AUTHOR: Oatley, Nick, PUBLISHER: Sage Publications (CA), This book is a comprehensive and authoritative account of the major realignment that has taken place in English regeneration policy and practice since . It analyzes the changes which have led to an emphasis in policy on competitiveness, integrated approaches to economic decline and social exclusion, and the shift away from formula-driven funding mechanisms towards controversial competitive bidding. It also examines changes in governance practices, the spread of multisector partnerships, the new localism' and the emergence of a contract culture. The book concludes with a summary of contemporary policy themes and an assessment of the Labour Government's policy proposals.

Behavioural Medicine in Cardiovascular Disorders

ISBN: , SKU: , AUTHOR: Behavioural Medicine in Cardio / Vaitl, D. / Langosch, W., PUBLISHER: John Wiley & Sons, Cardiovascular disorders are the major cause of death in the industrialized world. Contributions to this volume take account of the social, behavioral, emotional, and personality factors associated with these diseases. Chapters outline basic psychophysiological mechanisms in the development of cardiovascular disorders and discuss recent results in the behavioral management of these conditions. Stressing practical implementation of techniques by the practitioner, the chapters fall into four sections: psychophysiological aspects of essential hypertension, behavioral management of hypertension, prevention and rehabilitation of coronary heart disease, and behavioral aspects of cardiac arrhythmia and related problems. Each of the four sections is preceded by an introduction which outlines the issues considered.

Intro to Scholarship in Modern

ISBN: , SKU: , AUTHOR: Nicholls, David G., PUBLISHER: Modern Language Association of America, In this collection of essays, distinguished scholars of language and literature acquaint upper-level students with the forms and practice of research and criticism in language and literature.

Polar Rearrangements

ISBN: , SKU: , AUTHOR: Harwood, L. M. / Harwood, Laurence M., PUBLISHER: Oxford University Press, USA, The general principles of polar rearrangements are brought together in this undergraduate chemistry text, which deals with all the major rearrangements involving electron-deficient atoms or charged intermediates. Reactions involving migration to electron-deficient carbon, nitrogen, oxygen and sulphur, and sigmatropic rearrangements involving polar species, are thus treated in a coherent and consistent manner. Clear discussions of the reaction mechanisms are followed by examples of synthetic applications providing a concise yet comprehensive account of the nature and importance of these processes.

Accountability Arrangements for Financial Sector Regulators

ISBN: , SKU: , AUTHOR: Hupkes, Eva H. G. / Quintyn, Marc / Taylor, Michael, PUBLISHER: International Monetary Fund, Policymakers are often reluctant to grant independence to the agencies that regulate and supervise the financial sector because of the fear that these agencies, with their wide-ranging responsibilities and powers, could become a law unto themselves. This pamphlet describes mechanisms for making regulatory agencies accountable not only to the government but also to the industry they supervise and the public at large, with examples from a range of countries.

Advances in Enzymology and Related Areas of Molecular

ISBN: , SKU: , AUTHOR: Meister, Alton, PUBLISHER: Wiley-Interscience, "Advances in Enzymology and Related Areas of Molecular Biology" is a seminal series in the field of biochemistry, offering researchers access to authoritative reviews of the latest discoveries in all areas of enzymology and molecular biology. These landmark volumes date back to , providing an unrivaled view of the historical development of enzymology. The series offers researchers the latest understanding of enzymes, their mechanisms, reactions and evolution, roles in complex biological process, and their application in both the laboratory and industry. Each volume in the series features contributions by leading pioneers and investigators in the field from around the world. All articles are carefully edited to ensure thoroughness, quality, and readability. With its wide range of topics and long historical pedigree, "Advances in Enzymology and Related Areas of Molecular Biology" can be used not only by students and researchers in molecular biology, biochemistry, and enzymology, but also by any scientist interested in the discovery of an enzyme, its properties, and its applications.

Shikimic Acid: Metabolism and Metabolites

ISBN: , SKU: , AUTHOR: Haslam, Edwin, PUBLISHER: John Wiley & Sons, Reflects extensive coverage of major synthetic developments over the last 20 years. Discusses both primary and secondary metabolites in relation to how they are influenced by shikimic acid. Includes such topics as synthetic organic chemistry, enzymology of the common pathways in which shikimic acid plays a key role, biosynthetic problems associated with secondary metabolism and molecular evolution.

Pathways of Eternity The Crossroads of Existence

ISBN: , SKU: , AUTHOR: Brian V Sukhoo, PUBLISHER: PublishAmerica Incorporated, NA Acquista Ora

International Perspectives on Social Work: Global Conditions

ISBN: , SKU: , AUTHOR: Lyons, Karen / Manion, Kathleen / Carlsen, Mary, PUBLISHER: Palgrave MacMillan, This book argues the necessity for social professionals working locally to equip themselves with knowledge of global mechanisms and cross-cultural issues. Local level examples include the increase in victims of trafficking or the effects of HIV/AIDS on some immigrant groups. International examples include the risk to children moving across borders, the growth of international pedophile networks, and the proliferation of terrorism.

The Clark: Selections from the Sterling and Francine Clark

ISBN: , SKU: , AUTHOR: Kern, Steven / Lovett, Jennifer G. / Fernandez, Rafael, PUBLISHER: Hudson Hills Press, Highlights of one of America's great small museums; paintings and sculpture (including masterpieces by the French Impressionists and Americans Cassatt, Homer, Remington, and Saregent), drawings and prints, decorative arts (including masterworks of silver), and illustrated books.

Embryos, Genes and Birth Defects

ISBN: , SKU: , AUTHOR: Ferretti, Patricia / Copp, Andrew / Tickle, Cheryll, PUBLISHER: John Wiley & Sons, The first edition of "Embryos, Genes and Birth Defects," edited by the late Peter Thorogood, was a radical new book aimed at bridging the gap between the medical disciplines of embryology and dysmorphology, and recent advances in cellular, molecular and developmental biology. This new edition remains unique in its breadth and brings up to date our understanding of birth defects and of the strategies utilized to gain such knowledge. It features new chapters on human cytogenetics, mutagenesis and the eyes and ears. The book presents key topics in developmental biology and explains how they provide the foundations for understanding clinical birth defects. The first six chapters introduce concepts and strategies adopted to elucidate developmental anomalies leading to birth defects. The book then focuses on specific organs and reviews the cellular and molecular mechanisms affecting their development and how disruption of these mechanisms by genetic or environmental factors may underlie certain birth defects. The chapters are concise and provide up-to-date coverage of topics in a format that is easily accessible and yet at the forefront of research. Written primarily for paediatricians, obstetricians, clinical geneticists and allied workers, this book guides the reader through the contribution of modern molecular biology to our understanding of human development. Developmental and cellular biologists will learn how errors in the cellular and genetic mechanism can lead to classical disorders, diseases and syndromes.

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