mechanisms and pathways of heterotrimeric g protein

Antibody Production

ISBN: , SKU: , AUTHOR: Glyn, Leonard Eleazar / Glynn, L. E. / Glynn, Leonard E., PUBLISHER: John Wiley & Sons, A practical guide to the production of antibodies. Describes the biosynthesis of antibody molecules by B lymphocytes and their progeny, the use of genetic markers in the elucidation of mechanisms of antibody synthesis, and of the generation of antibody diversity. Also deals with anomalies in antibody production which result in immunoglobulinopathies, involving qualitative or quantitative abnormalities, or both, in the immunoglobulins.

Immunology: A Short Course

ISBN: , SKU: , AUTHOR: Coico, Richard / Sunshine, Geoffrey, PUBLISHER: Wiley-Blackwell, "Immunology: A Short Course, Sixth Edition" introduces all the critical topics of modern immunology in clear and succinct yet comprehensive fashion. The authors offer a uniquely balanced coverage of classical and contemporary approaches, basic and clinical aspects. As with the previous editions, the strength of the text is in a complete review of modern immunology without burdening the reader with excessive data or theoretical discussions. Each chapter is divided into short, self-contained units that address key topics illustrated by uniformly drawn, full-color illustrations, many brand new to this edition. The sixth edition of this successful textbook newly covers: Toll-like receptors, their ligands and intracellular activation pathways The key role of activation induced cytidine deaminase (AID) in somatic hypermutation and class switch recombination. The autoimmune regulator ("AIRE)" gene in self-tolerance and autoimmunity T and B cell activation and the immunological synapse, as well as characterization and mechanisms of action of T regulatory cells Praise for the previous edition: "This book is clearly a precious resource for undergraduate, graduate and medical students alike... For those who need an introduction to the fascinating world of immunology, this book should most certainly spark the interest." "ANNALS OF BIOMEDICAL ENGINEERING"..". an excellent beginner's guide... the authors have done a terrific job of providing an overview of the field." "YALE JOURNAL OF BIOLOGY AND MEDICINE"

Computational Approaches to Morphology and Syntax

ISBN: , SKU: , AUTHOR: Roark, Brian / Sproat, Richard, PUBLISHER: Oxford University Press, USA, The book will appeal to scholars and advanced students of morphology, syntax, computational linguistics and natural language processing (NLP). It provides a critical and practical guide to computational techniques for handling morphological and syntactic phenomena, showing how these techniques have been used and modified in practice. The authors discuss the nature and uses of syntactic parsers and examine the problems and opportunities of parsing algorithms for finite-state, context-free and various context-sensitive grammars. They relate approaches for describing syntax and morphology to formal mechanisms and algorithms, and present well-motivated approaches for augmenting grammars with weights or probabilities.

Pathways to Cultural Awareness: Cultural Therapy with

ISBN: , SKU: , AUTHOR: Spindler, George D. / Spindler, George / Spindler, Louise, PUBLISHER: Corwin Press, Cultural therapy is a way of helping people cope with cultural diversity and societal inequity through the mediation of the school as a central institution for cultural transmission and maintenance. This book illustrates how cultural therapy can be applied in educational settings to promote better understanding among teachers and students. Each chapter presents a situation in which the author has been intimately involved, offering a variety of approaches to, and interpretations of, cultural therapy.

Oatley: Cities, Economic (P) Competition and Urban Policy

ISBN: , SKU: , AUTHOR: Oatley, Nick, PUBLISHER: Sage Publications (CA), This book is a comprehensive and authoritative account of the major realignment that has taken place in English regeneration policy and practice since . It analyzes the changes which have led to an emphasis in policy on competitiveness, integrated approaches to economic decline and social exclusion, and the shift away from formula-driven funding mechanisms towards controversial competitive bidding. It also examines changes in governance practices, the spread of multisector partnerships, the new localism' and the emergence of a contract culture. The book concludes with a summary of contemporary policy themes and an assessment of the Labour Government's policy proposals.

Behavioural Medicine in Cardiovascular Disorders

ISBN: , SKU: , AUTHOR: Behavioural Medicine in Cardio / Vaitl, D. / Langosch, W., PUBLISHER: John Wiley & Sons, Cardiovascular disorders are the major cause of death in the industrialized world. Contributions to this volume take account of the social, behavioral, emotional, and personality factors associated with these diseases. Chapters outline basic psychophysiological mechanisms in the development of cardiovascular disorders and discuss recent results in the behavioral management of these conditions. Stressing practical implementation of techniques by the practitioner, the chapters fall into four sections: psychophysiological aspects of essential hypertension, behavioral management of hypertension, prevention and rehabilitation of coronary heart disease, and behavioral aspects of cardiac arrhythmia and related problems. Each of the four sections is preceded by an introduction which outlines the issues considered.

Intro to Scholarship in Modern

ISBN: , SKU: , AUTHOR: Nicholls, David G., PUBLISHER: Modern Language Association of America, In this collection of essays, distinguished scholars of language and literature acquaint upper-level students with the forms and practice of research and criticism in language and literature.

Polar Rearrangements

ISBN: , SKU: , AUTHOR: Harwood, L. M. / Harwood, Laurence M., PUBLISHER: Oxford University Press, USA, The general principles of polar rearrangements are brought together in this undergraduate chemistry text, which deals with all the major rearrangements involving electron-deficient atoms or charged intermediates. Reactions involving migration to electron-deficient carbon, nitrogen, oxygen and sulphur, and sigmatropic rearrangements involving polar species, are thus treated in a coherent and consistent manner. Clear discussions of the reaction mechanisms are followed by examples of synthetic applications providing a concise yet comprehensive account of the nature and importance of these processes.

Accountability Arrangements for Financial Sector Regulators

ISBN: , SKU: , AUTHOR: Hupkes, Eva H. G. / Quintyn, Marc / Taylor, Michael, PUBLISHER: International Monetary Fund, Policymakers are often reluctant to grant independence to the agencies that regulate and supervise the financial sector because of the fear that these agencies, with their wide-ranging responsibilities and powers, could become a law unto themselves. This pamphlet describes mechanisms for making regulatory agencies accountable not only to the government but also to the industry they supervise and the public at large, with examples from a range of countries.

Advances in Enzymology and Related Areas of Molecular

ISBN: , SKU: , AUTHOR: Meister, Alton, PUBLISHER: Wiley-Interscience, "Advances in Enzymology and Related Areas of Molecular Biology" is a seminal series in the field of biochemistry, offering researchers access to authoritative reviews of the latest discoveries in all areas of enzymology and molecular biology. These landmark volumes date back to , providing an unrivaled view of the historical development of enzymology. The series offers researchers the latest understanding of enzymes, their mechanisms, reactions and evolution, roles in complex biological process, and their application in both the laboratory and industry. Each volume in the series features contributions by leading pioneers and investigators in the field from around the world. All articles are carefully edited to ensure thoroughness, quality, and readability. With its wide range of topics and long historical pedigree, "Advances in Enzymology and Related Areas of Molecular Biology" can be used not only by students and researchers in molecular biology, biochemistry, and enzymology, but also by any scientist interested in the discovery of an enzyme, its properties, and its applications.

Shikimic Acid: Metabolism and Metabolites

ISBN: , SKU: , AUTHOR: Haslam, Edwin, PUBLISHER: John Wiley & Sons, Reflects extensive coverage of major synthetic developments over the last 20 years. Discusses both primary and secondary metabolites in relation to how they are influenced by shikimic acid. Includes such topics as synthetic organic chemistry, enzymology of the common pathways in which shikimic acid plays a key role, biosynthetic problems associated with secondary metabolism and molecular evolution.

Pathways of Eternity The Crossroads of Existence

ISBN: , SKU: , AUTHOR: Brian V Sukhoo, PUBLISHER: PublishAmerica Incorporated, NA Acquista Ora

International Perspectives on Social Work: Global Conditions

ISBN: , SKU: , AUTHOR: Lyons, Karen / Manion, Kathleen / Carlsen, Mary, PUBLISHER: Palgrave MacMillan, This book argues the necessity for social professionals working locally to equip themselves with knowledge of global mechanisms and cross-cultural issues. Local level examples include the increase in victims of trafficking or the effects of HIV/AIDS on some immigrant groups. International examples include the risk to children moving across borders, the growth of international pedophile networks, and the proliferation of terrorism.

The Clark: Selections from the Sterling and Francine Clark

ISBN: , SKU: , AUTHOR: Kern, Steven / Lovett, Jennifer G. / Fernandez, Rafael, PUBLISHER: Hudson Hills Press, Highlights of one of America's great small museums; paintings and sculpture (including masterpieces by the French Impressionists and Americans Cassatt, Homer, Remington, and Saregent), drawings and prints, decorative arts (including masterworks of silver), and illustrated books.

Embryos, Genes and Birth Defects

ISBN: , SKU: , AUTHOR: Ferretti, Patricia / Copp, Andrew / Tickle, Cheryll, PUBLISHER: John Wiley & Sons, The first edition of "Embryos, Genes and Birth Defects," edited by the late Peter Thorogood, was a radical new book aimed at bridging the gap between the medical disciplines of embryology and dysmorphology, and recent advances in cellular, molecular and developmental biology. This new edition remains unique in its breadth and brings up to date our understanding of birth defects and of the strategies utilized to gain such knowledge. It features new chapters on human cytogenetics, mutagenesis and the eyes and ears. The book presents key topics in developmental biology and explains how they provide the foundations for understanding clinical birth defects. The first six chapters introduce concepts and strategies adopted to elucidate developmental anomalies leading to birth defects. The book then focuses on specific organs and reviews the cellular and molecular mechanisms affecting their development and how disruption of these mechanisms by genetic or environmental factors may underlie certain birth defects. The chapters are concise and provide up-to-date coverage of topics in a format that is easily accessible and yet at the forefront of research. Written primarily for paediatricians, obstetricians, clinical geneticists and allied workers, this book guides the reader through the contribution of modern molecular biology to our understanding of human development. Developmental and cellular biologists will learn how errors in the cellular and genetic mechanism can lead to classical disorders, diseases and syndromes.

Franceschi, Crepaldi, et al. Aging and Cellular Defense

Libro Franceschi, Crepaldi, Cristofalo, Vijg. Aging and Cellular Defense Mechanisms. Annals N.Y. Academy of Science vol , pag 526 con numerose figure. Nuovo.Inclusa spedizione come piego di libri.

Crystallographic Computing 3: Data Collection, Structure

ISBN: , SKU: , AUTHOR: Sheldrick, G. M. / Kruger, C. / Goddard, R., PUBLISHER: Oxford University Press, USA, The latest in a series on crystallographic computing, this collection of 33 papers covers the full spectrum of computer applications in crystallography, including the use of micro-, mini-, and mainframe computers. Special emphasis is given to single crystal and powder data collection, including position sensitive detectors; to crystallographic databases; to computer methods in protein crystallography; and to program systems for crystal structure determination. Presented at the Ninth International School on Crystallographic Computing, held in Mulheim (FRG) in August , these papers provide state-of-the-art information that is not available elsewhere.

Libro Franceschi, Crepaldi, Cristofalo, Vijg. Aging and Cell

Libro Franceschi, Crepaldi, Cristofalo, Vijg. Aging and Cellular Defense Mechanisms. Annals N.Y. Academy of Science vol , pag 526 con numerose figure. Nuovo. Spedizione ordinaria inclusa

Clocks and Clock Repairing

ISBN: , SKU: , AUTHOR: Smith, Eric, PUBLISHER: Lutterworth Press, A simple and straightforward guide to the internal working and repair of clocks, modern and antique. Eric Smith's clear guide mechanisms, fault diagnosis and repair of clocks has established itself as an excellent reference for anyone interested in this fascinating and rewarding hobby. The ten chapters go through the practical stages of how different types of clock work, and the tools and materials needed to repair them. Pendulum clocks, 30-hour, 8-day, and 400-hour clocks, chiming, striking, quartz, electric and alarm clocks are all covered in detail. A final chapter is included on working with more advanced tool, such as lathes. Extensively illustrated with photographs and diagrams. Also available, by the same author: Clocks: A Guide for Owners, ISBN

Breathing Disorders in Sleep

ISBN: , SKU: , AUTHOR: McNicholas, Walter / Phillipson, Eliot A. / Wb Saunders Company, Saunders Company, PUBLISHER: W.B. Saunders Company, Breathing Disorders in Sleep is an authorative reference for all those involved in the clinical investigation and care of patients with sleep-related respiratory disorders. Information is provided in a logical sequence, divided initially into Physiology and Pathophysiology of Sleep and Respiration, Sleep Apnoea and Sleep in Other Respiratory Disorders. From the foundation mechanisms involved, followed by clinical presentation through to management, clinical investigation and diagnosis, McNicholas and Phillipson have defined the current state-of-the-art in a rapidly growing and increasingly complex area.

Radio Wave Propagation for Telecommunication Applications

ISBN: , SKU: , AUTHOR: Sizun, Herve / Sizun, Herv / Fornel, P. De, PUBLISHER: Springer, This books thoroughly describes the physical mechanisms of electromagnetic wave propagation in the terrestrial and near space environment. It thus provides advanced students and development engineers the background for the design of reliable telecommunication systems in the radiofrequency domain.

Additives and Crystallization Processes: From Fundamentals

ISBN: , SKU: , AUTHOR: Sangwal, Keshra, PUBLISHER: John Wiley & Sons, Crystal growth technology involves processes for the production of crystals essential for microelectronics, communication technologies, lasers and energy producing and energy saving technology. A deliberately added impurity is called an additive and in different industries these affect the process of crystal growth. Thus, understanding of interactions between additives and the crystallizing phases is important in different processes found in the lab, nature and in various industries. This book presents a generalized description of the mechanisms of action of additives during nucleation, growth and aggregation of crystals during crystallization and has received endorsement from the President of the International Organization for Crystal Growth. It is the first text devoted to the role of additives in different crystallization processes encountered in the lab, nature and in industries as diverse as pharmaceuticals, food and biofuels. A unique highlight of the book are chapters on the effect of additives on crystal growth processes, since the phenomena discussed is an issue of debate between researchers

Pediatric Care Planning

ISBN: , SKU: , AUTHOR: Speer, Kathleen Morgan / Speer, PUBLISHER: Lippincott Williams & Wilkins, New in this edition are sample clinical pathways; plans of care for tuberculosis; interventions and rationales related to patient outcomes; assessment findings by body system; and updated NANDA taxonomy and JCAHO standards. Contents include contributors and reviewers; acknowledgments; preface; introduction; respiratory system; cardiovascular system; neurologic system; gastrointestinal and hepatobiliary systems; genitourinary system; musculoskeletal system; eye, ear, nose, and throat; hematologic and immunologic systems; endocrine system; psychosocial and other problems; perioperative care; diagnostic studies; home health care; appendices, including normal growth and development, normal vital sign measurements, physical growth charts, NANDA taxonomy of nursing diagnoses, normal laboratory values, and guide to food values; selected references; and index. A Brandon-Hill Recommended Title.

Inheritance Hierarchies in Knowledge Representation and

ISBN: , SKU: , AUTHOR: Lenzerini, Maurizio / Simi, Maria / Nardi, Daniele, PUBLISHER: John Wiley & Sons, This work serves as an introduction to the research on inheritance hierarchies and a collection of some technical presentations of recent developments in the field. Among the topics covered are: taxonomic reasoning, mixed inheritance, the relationship between inheritance and knowledge representation, inheritance networks, inheritance in object oriented programming languages, partial equivalence relations, inheritance mechanisms in the OBJLOG language, horn clause theories, and logic programming knowledge bases.

Researching the People's Health

ISBN: , SKU: , AUTHOR: Williams, G. / Popay, Jennie / Williams, Gareth, PUBLISHER: Routledge, "Researching the People's Health" examines two related issues: the role of social research in the rapidly changing world of health services, and the relationship between lay and expert knowledge in public health and health care. The book examines these issues against the background of long-term transformations in patterns of health and illness and rapid changes in the strategic management and commissioning of health services. In doing so the book makes a contribution to the continuing and urgent debates on the assessment of health needs, the organization and delivery of health care, and the politics of health service organization and funding.

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