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Cardiac Safety of Noncardiac Drugs: Practical Guidelines for

ISBN: , SKU: , AUTHOR: Morganroth, Joel / Gussak, Ihor, PUBLISHER: Humana Press, Basic and clinical researchers from industry and academia detail the preclinical, clinical, and regulatory principles currently used to assess the cardiac safety of new drugs. The authors explain the parameters of cardiac safety at all stages of clinical research and drug development, including both the preclinical and pharmacogenomic aspects generally and the clinical methodologies and technical aspects for investigational drugs based on cardiac repolarization, as defined by the duration of the QTc interval. Additional chapters comprehensively review the application of electrocardiography in clinical research, the fundamentals of ECG interpretation in clinical trials, the statistical analysis plans for ECG data obtained in formal clinical trials, and the practical interpretation of the ECG results. Highlights include practical guidance on how to conduct a thorough ECG Trial in New Drug Development, how to use new ECG and web based technology in clinical research, and how to follow the new FDA requirements for ECG submissions.

Tunnels and Shafts in Rock

ISBN: , SKU: , AUTHOR: U. S. Army Corps of Engineers / U. S. Army Corps of Engineers, Army Corps of Engineers, PUBLISHER: University Press of the Pacific, This manual was prepared by the U.S. Army Corps of Engineers and provides technical criteria and guidance for the planning, design, and construction of tunnels and shafts in rock for civil works projects. Specific areas covered include geological and geotechnical explorations required, construction of tunnels and shafts, design considerations, geomechanical analysis, design of linings, and instrumentation and monitoring. The manual emphasizes design, construction and an understanding of the methods, and conditions of construction essential to the preparation of good designs.

For Honor

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The Economic Person: Acting and Analyzing

ISBN: , SKU: , AUTHOR: Danner, Peter L., PUBLISHER: Rowman & Littlefield Publishers, This book emphasizes that analysis of broad economic changes treats people abstractly, while a personalist view sees them as human agents who, while needing and generating economic goods, must still be responsive to others and be aware of values and goals beyond temporal well-being. Visit our website for sample chapters

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Patent Applications: A Tool for Identifying Advances in

ISBN: , SKU: , AUTHOR: DeRosa, Thomas F., PUBLISHER: John Wiley & Sons, Covering patent literature and process improvements in twenty-two polymer subject areas, this book provides researchers with current polymer research not yet published in journals or patents. Moreover, the review and analysis by the author provides a more thorough understanding and concise package of the patent application. It offers a reference that ranges from monomer preparation to polymer characterization and properties. "Polymer Chemistry Advances in US Patent Application"s provides a practical approach for readers to identify research and market trends, and stay up-to-date on current developments in the field.

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Ecoregion-Based Design for Sustainability

ISBN: , SKU: , AUTHOR: Bailey, Robert G. / Ropes, L. G., PUBLISHER: Springer, This richly illustrated volume completes Robert G. Bailey's celebrated study of ecoregions, begun in the landmark Ecosystem Geography () and further articulated in Ecoregions (). In this third installment, the author expands his system for defining large-scale ecological zones to encompass principles of land management, regional planning, and design. In an engaging, nontechnical discussion, he shows how larger patterns and processes that characterize a region--its climate, topography, soils, vegetation, fauna, and human culture--provide essential keys to the sustainability of ecosystems. Ecoregion-Based Design for Sustainability will be welcomed by land and resource managers, landscape architects and urban planners, ecologists, students, and anyone interested in ecology-based design. "Bob Bailey is] the man behind the ecosystem mapping of the world." -Lingua Franca Reviews of Ecoregions: "The book provides easy access to the geographic distribution, characteristics, and processes operating behind every major ecosystem in the world." -Geoscience Canada "Ecoregions offers an invaluable source of description, interpretation and analysis of global patterns of ecosystem distribution and successfully provides the reader with a means of making sense of these patterns." -Geography Robert G. Bailey is a geographer with the United States Forest Service in Fort Collins, Colorado. Formerly the leader of the agency's Ecosystem Management Analysis Center, he is currently in charge of ecoregion studies at the Inventory and Monitoring Institute.

Technical Analysis, Study Guide

ISBN: , SKU: , AUTHOR: Jack D Schwager, PUBLISHER: Wiley, NA

Analysis 2 1st Edition

ISBN: , SKU: , AUTHOR: Christian Blatter, PUBLISHER: Springer Verlag, NA

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The Heart of Yoga: Developing a Personal Practice

ISBN: , SKU: , AUTHOR: Desikachar, T. K. V., PUBLISHER: Inner Traditions International, The first yoga text to outline a step-by-step sequence for developing a complete practice according to viniyoga--yoga adapted to the needs of the individual. - A contemporary classic by a world-renowned teacher. - This new edition adds thirty-two poems by Krishnamacharya that capture the essence of his teachings. Sri Tirumalai Krishnamacharya, who lived to be over 100 years old, was one of the greatest yogis of the modern era. Elements of Krishnamacharya's teaching have become well known around the world through the work of B. K. S. Iyengar, Pattabhi Jois, and Indra Devi, who all studied with Krishnamacharya. Krishnamacharya's son T. K. V. Desikachar lived and studied with his father all his life and now teaches the full spectrum of Krishnamacharya's yoga. Desikachar has based his method on Krishnamacharya's fundamental concept of "viniyoga," which maintains that practices must be continually adapted to the individual's changing needs to achieve the maximum therapeutic value. In "The Heart of Yoga" Desikachar offers a distillation of his father's system as well as his own practical approach, which he describes as "a program for the spine at every level--physical, mental, and spiritual." This is the first yoga text to outline a step-by-step sequence for developing a complete practice according to the age-old principles of yoga. Desikachar discusses all the elements of yoga--poses and counterposes, conscious breathing, meditation, and philosophy--and shows how the yoga student may develop a practice tailored to his or her current state of health, age, occupation, and lifestyle. This is a revised edition of "The Heart of Yoga."

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Stochastic Processes in the Neurosciences

ISBN: , SKU: , AUTHOR: Tuckwell, Henry C., PUBLISHER: Society for Industrial and Applied Mathematic, This monograph is centered on quantitative analysis of nerve-cell behavior. The work is foundational, with many higher order problems still remaining, especially in connection with neural networks. Thoroughly addressed topics include stochastic problems in neurobiology, and the treatment of the theory of related Markov processes.

Sudden Death in Infancy, Childhood and Adolescence

ISBN: , SKU: , AUTHOR: Byard, Roger W., PUBLISHER: Cambridge University Press, This volume provides a comprehensive, authoritative summary of the many causes, clinical manifestations, and forensic indicators of sudden death in infants, children, and adolescents. The authors present a detailed analysis of the many disorders responsible for sudden death in this age group, including both accidental and non-accidental trauma, cardiac, respiratory, and neurological conditions, infections, and Sudden Infant Death Syndrome. The authors also provide an autopsy manual with specific investigative procedures for a number of different cases of sudden death. Extensively illustrated and embellished with interesting historical notes, this unique interdisciplinary text will be an indispensable reference.

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The New Teacher's Companion: Practical Wisdom for Succeeding

ISBN: , SKU: , AUTHOR: Cunningham, Gini, PUBLISHER: Association for Supervision & Curriculum Deve, Advice for new teacher excellence, including guidance on classroom management.

Sales Management: Analysis and Decision Making

ISBN: , SKU: , AUTHOR: Schwepker, Charles H. / LaForge, Raymond W. / Ingram, Thomas N., PUBLISHER: Houghton Mifflin Harcourt (HMH), This leading text continues to set the standard in sales management texts with its up-to-the-minute coverage of the trends and issues in the dynamic sales field, equipping students with a strong sales foundation and the innovative skills needed for 21st century selling.

Roots of Revolution: Radical Thought in Cuba

ISBN: , SKU: , AUTHOR: Liss, Sheldon B., PUBLISHER: University of Nebraska Press, Concerned with what Cuban radicals have thought about their na-tion's protracted struggle for independence, Sheldon B. Liss looks at each one's mode of analysis, position on the class struggle, ideas on reform or revolution, and search for community. Each writer's beliefs about ethics, morality, religion, social mobility, political control, aesthetics, and quality of life are subjected to scrutiny by Liss. He also considers their views on Cuban-United States relations, their perceptions of the state and power, and their relationships to the means of production and workers' movements.

Exquisite Specificity: The Monoclonal Antibody Revolution

ISBN: , SKU: , AUTHOR: Cambrosio, Keating / Cambrosio, Alberto / Keating, Peter, PUBLISHER: Oxford University Press, USA, In Cesar Milstein and Georges Kohler were awarded the Nobel Prize for their discovery of "hybridoma technology," a method leading to the production of unlimited quantities of biological reagents of "exquisite specificity" known as monoclonal antibodies. Focusing on this ground-breaking development in the recent history of the biomedical sciences, this volume offers a description of scientific activity that delineates the development of scientific knowledge. Based on an extensive reading of the literature in the field, interviews with leading participants and on-site observation, the book follows events, materials and actors through a twenty-year period during which a laboratory technique was transformed into one of the most successful tools of modern biotechnology. Beginning with an analysis of the amiguities surrounding the initial status of monoclonal antibodies, the book goes on to explore the various practices and forms of knowledge involved in the reproduction of hybridoma technology. The analysis of the worldwide diffusion of monoclonal antibodies and their consequent transformatin by users is complemented with a close-up account of their adoption within two laboratories. The book ends with a detailed analysis of the patent disputes that have shaped the industrial destiny of monoclonal antibodies. Acquista Ora

Tourism Today A Geographical Analysis

ISBN: , SKU: , AUTHOR: G Douglas, PUBLISHER: Longman Group, NA

The Elements of Practical Psycho-Analysis

ISBN: , SKU: , AUTHOR: Bousfield Paul, PUBLISHER: Routledge, NA

All about Futures: The Easy Way to Get Started

ISBN: , SKU: , AUTHOR: Wasendorf, Russell R., Sr. / Wasendorf Russell, PUBLISHER: McGraw-Hill, Since 's first edition of this bestselling book, the futures market has changed incredibly--Internet access and electronic trading dominate the market, options have grown in importance, and a greater number of futures markets exist worldwide. All About Futures, Second Edition, covers all the updated basics of futures trading for the beginner, and illustrates trading strategies from the simple to the complex for experienced traders who need to brush up on their skills. An integral element in McGraw-Hill's All About series, this completely revised and updated book discusses: *Detailed Internet strategies for effective electronic trading *Basic approaches to technical analysis and anticipating price direction *Insights on working with a broker and developing a trading strategy

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