exquisite specificity the monoclonal antibody revolution

Exquisite Specificity: The Monoclonal Antibody Revolution

ISBN: , SKU: , AUTHOR: Cambrosio, Keating / Cambrosio, Alberto / Keating, Peter, PUBLISHER: Oxford University Press, USA, In Cesar Milstein and Georges Kohler were awarded the Nobel Prize for their discovery of "hybridoma technology," a method leading to the production of unlimited quantities of biological reagents of "exquisite specificity" known as monoclonal antibodies. Focusing on this ground-breaking development in the recent history of the biomedical sciences, this volume offers a description of scientific activity that delineates the development of scientific knowledge. Based on an extensive reading of the literature in the field, interviews with leading participants and on-site observation, the book follows events, materials and actors through a twenty-year period during which a laboratory technique was transformed into one of the most successful tools of modern biotechnology. Beginning with an analysis of the amiguities surrounding the initial status of monoclonal antibodies, the book goes on to explore the various practices and forms of knowledge involved in the reproduction of hybridoma technology. The analysis of the worldwide diffusion of monoclonal antibodies and their consequent transformatin by users is complemented with a close-up account of their adoption within two laboratories. The book ends with a detailed analysis of the patent disputes that have shaped the industrial destiny of monoclonal antibodies. Acquista Ora

Antibody Production

ISBN: , SKU: , AUTHOR: Glyn, Leonard Eleazar / Glynn, L. E. / Glynn, Leonard E., PUBLISHER: John Wiley & Sons, A practical guide to the production of antibodies. Describes the biosynthesis of antibody molecules by B lymphocytes and their progeny, the use of genetic markers in the elucidation of mechanisms of antibody synthesis, and of the generation of antibody diversity. Also deals with anomalies in antibody production which result in immunoglobulinopathies, involving qualitative or quantitative abnormalities, or both, in the immunoglobulins.

The French Revolution:

ISBN: , SKU: , AUTHOR: Jones, Peter, PUBLISHER: Longman, "This book, the latest in the best-selling Seminar Studies in History series, provides readers with an accessible and succinct introduction to the French Revolution, one of the most exciting and important periods in modern history. The author examines the events leading up to the revolution, the revolution itself, and the aftermath. The Assessment and Documents sections of the book will be particulalry helpful for the reader to understanding the French Revolution For those interested in French History or the French Revolution

The Global Technology Revolution

ISBN: , SKU: , AUTHOR: Anton, Philip S. / Silberglitt, Richard / Schneider, James, PUBLISHER: RAND Corporation, Beyond the agricultural and industrial revolutions of the past, a global technology revolution is currently changing the world. This book discusses the broad, mulitdisciplinary, and synergistic trends in this revolution, including genomics, cloning, biom

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Revolutions and the Revolutionary Tradition: In the West

ISBN: , SKU: , AUTHOR: Parker, David, PUBLISHER: Routledge, Presents eight European case studies including the English revolution of , the French Revolution and the recent revolutions within the Soviet Union and Eastern Europe () and examines them not only in their specific political, economic and social contexts but also as part of the wider European revolutionary tradition. A chapter on the American Revolution is also included as a revolution which grew out of a European expansionist and a European political culture. David Parker brings together leading writers on European history, who make a major contribution to the controversial debate on the role of revolution in the development of European history. This is a truly comparative book which includes discussion on each of the following key themes: *the causes of revolution, including the importance of political, social and economic factors *the effects of political and philisophical ideas or ideology on the revolution *the form and process of a revolution, including the importance of violence and popular support *the outcome of revolution, both short-term and long-term *the way revolution is viewed in history particularly since the collapse of Communism in Europe As well as providing new historical perspectives on the concept of revolution, this book also provides a comparative survey of all the major revolutions in the West over the past 400 years.

Who Was Who in the American Revolution

ISBN: , SKU: , AUTHOR: Purcell, L. Edward, PUBLISHER: Facts on File, Containing over entries, this is the first one-volume reference to examine the lives and careers of the men and women of the Revolution. The book covers the full spectrum of historical figures, including regular army and military generals, naval commanders, significant civilians, Loyalists, French allies, diplomats, and more.

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