peptide based drug design

Peptide-Based Drug Design

ISBN: , SKU: , AUTHOR: Otvos Jr, Laszlo / Otvos, Laszlo, PUBLISHER: Humana Press, Due to their high specificity and low toxicity profile, peptides have once again become central to the development of new drugs. In Peptide-Based Drug Design: Methods and Protocols, expert researchers provide a handbook which offers a selection of research and production tools suitable for transforming a promising protein fragment or stand-alone native peptide into a pharmaceutically acceptable composition. The volume delves into contemporary, cutting-edge subjects such as hit isolation and target validation, computer-aided design, sequence modifications to satisfy pharmacologists, in vivo stability and imaging, and the actual production of difficult sequences. Written in the highly successful Methods in Molecular Biologya" series format, chapters include readily reproducible, step-by-step laboratory protocols, lists of materials, and the Notes section, which highlights tips on troubleshooting and avoiding known pitfalls. Comprehensive and up-to-date, Peptide-Based Drug Design: Methods and Protocols shows its subject to be an independent science on the rise, and provides scientists with a clear, concise guide for continuing this vital research. Acquista Ora

Idiosyncratic Adverse Drug Reactions Impact on Drug

ISBN: , SKU: , AUTHOR: C A Naranjo J K Jones, PUBLISHER: Excerpta Medica, NA Acquista Ora

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Nurse's Clinical Guide: Dosage Calculations

ISBN: , SKU: , AUTHOR: Erickson, Belle / Todd, Catherine M. / Erickson, PUBLISHER: Lippincott Williams & Wilkins, This guide covers drug labels and the latest drug delivery methods, such as fentanyl patches and needleless injections. Also included is a review of dimensional analysis. In addition, nurses find a refresher of math and basic dosage principles, considerations for special-needs patients, and practice exercises. Contents include a review of mathematics; systems of drug measurements; the administration process; calculating enteral drug dosages; calculating parenteral drug dosages; solutions, ointments, and patches; other considerations; appendices; references; index.

Sexed Work: Gender, Race, and Resistance in a Brooklyn Drug

ISBN: , SKU: , AUTHOR: Maher, Lisa, PUBLISHER: Oxford University Press, USA, Based on three years of ethnographic work in New York City, this book provides the first detailed account of the economic lives of women drug users. Set in a neighborhood plagued with AIDS, Sexed Work reveals the economic lives of a group of women whose options have been severely circumscribed, not only by drug use, but also by poverty, racism, violence, and enduring marginality. Maher draws extensively on the women's own words to describe how structures and relations of gender, race and class are articulated by divisions of labor in the street-level drug economy. This rich, nuanced and theoretically sophisticated study of "crime as work" will be compelling reading for all those interested in the way in which women deal with the intersection of gender, race, and work.

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Litt's Drug Eruption Reference Manual Including Drug

ISBN: , SKU: , AUTHOR: Litt, Jerome Z., PUBLISHER: Informa Healthcare, The most widely acclaimed book for practitioners is even further expanded and improved. A must for every doctor's office - and for hospital consultations - the edition of this groundbreaking resource covers the side effects that can develop from the use of recently approved as well as commonly prescribed medications, OTC drugs, herbals, and supplements. The easy-to-use alphabetic format and wealth of evidence-based information make this book and CD-ROM combination an essential resource for all physicians.

Drug Interaction Facts& #;: Published by Facts and

ISBN: , SKU: , AUTHOR: Tatro, David S. / Published by Facts and Comparisons, PUBLISHER: Lippincott Williams & Wilkins, This comprehensive reference includes clinically significant drug interactions as well as interactions that are suspected but unsubstantiated. Every monograph includes a concise synopsis of the onset, severity and documentation of the drug interaction. The comprehensive index permits rapid screening for potential interactions by class, generic drug or trade name. All information has been thoroughly reviewed and evaluated by an interdisciplinary panel of experts.

Drug Facts and Comparisons: Pocket Version

ISBN: , SKU: , AUTHOR: Facts & Comparisons, PUBLISHER: Lippincott Williams & Wilkins, Drug Facts and Comparisons: Pocket Version is the ideal resource for the drug information you need at the point of care. Abridged from Drug Facts and Comparisons, this handy pocket version allows you to confirm critical drug information immediately, in a quick-reference format. Pocket DFC features the most commonly used drugs, conveniently addressing topics that demand attention. Features include: Rx and OTC drugs; similar products listed together in tables for easy comparison; more than brand name and 600 generic drugs; dozens of convenient charts; and more than 300 monographs.

Cardiac Safety of Noncardiac Drugs: Practical Guidelines for

ISBN: , SKU: , AUTHOR: Morganroth, Joel / Gussak, Ihor, PUBLISHER: Humana Press, Basic and clinical researchers from industry and academia detail the preclinical, clinical, and regulatory principles currently used to assess the cardiac safety of new drugs. The authors explain the parameters of cardiac safety at all stages of clinical research and drug development, including both the preclinical and pharmacogenomic aspects generally and the clinical methodologies and technical aspects for investigational drugs based on cardiac repolarization, as defined by the duration of the QTc interval. Additional chapters comprehensively review the application of electrocardiography in clinical research, the fundamentals of ECG interpretation in clinical trials, the statistical analysis plans for ECG data obtained in formal clinical trials, and the practical interpretation of the ECG results. Highlights include practical guidance on how to conduct a thorough ECG Trial in New Drug Development, how to use new ECG and web based technology in clinical research, and how to follow the new FDA requirements for ECG submissions.

Refusal Skills: Preventing Drug Use in Adolescents

ISBN: , SKU: , AUTHOR: Goldstein, Arnold P. / Amann, Lester L. / Reagles, Kenneth W., PUBLISHER: Research Press (IL), Based on the Skillstreaming approach, this book provides a step-by-step method for teaching adolescents the skills they need to effectively refuse drugs and alcohol.

Mosby's Handbook of Drug-Herb and Drug-Supplement

ISBN: , SKU: , AUTHOR: Health Gate Data Corporation / Harness, Richard / Bratman, Stven, PUBLISHER: Mosby, With an increasing number of patients combining herbal treatments with prescribed medications, reliable information on herb/supplement and pharmaceutical interactions is much needed. This portable reference is organized alphabetically by drug name and features an entry for each drug-herb/drug-supplement combination that has a proven interaction. Each entry is rated on a scale of 1 to 4 to show the severity of the interaction and includes information on related drugs, an interaction summary, a discussion of the interaction, management suggestions, and references. In addition to the core material, there are also several helpful appendices on interactions by herb or supplement, nutrient depletions, and drug-herb add-on depressant interactions.

Manga Lowful drugstore

Lowful drugstore vol 3 6 euro Titolo Originale: Goho Drug Titolo Inglese: Legal Drug Storia: CLAMP, Ohkawa Ageha Disegni: CLAMP, Nekoi Tsubaki Edit. Originale: Kadokawa Shoten Tipologia: Shoujo, Shounen-Ai Genere: Soprannaturale, Mistero

Clinician's Pocket Drug Reference

ISBN: , SKU: , AUTHOR: Gomella, Leonard G. / Haist, Steven A. / Gelhot Adams, Aimee, PUBLISHER: McGraw-Hill Companies, QUICK, RELIABLE, AND REVISED ANNUALLY This quick access guide covers more than of the most commonly used medications. Organized alphabetically by generic drug name, each entry includes selected key data such as common uses, contraindications, and common side effects. The manual also provides a list of the medications organized by drug classification.

Practical Drug Enforcement, Second Edition

ISBN: , SKU: , AUTHOR: Lyman, Michael D. / Lyman, Lyman D., PUBLISHER: CRC Press, Practical Drug Enforcement, Second Edition offers an incisive look at the technical methods required to conduct successful drug investigations. It explores specific enforcement problems, such as marijuana cultivation, clandestine laboratories, crack houses, booby traps, and raid planning. This second edition has been thoroughly updated, and it discusses contemporary concerns, recent case studies, and new developments in the law.

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The Search for Rational Drug Control

ISBN: , SKU: , AUTHOR: Zimring, Franklin E. / Hawkins, Gordon, PUBLISHER: Cambridge University Press, This book presents a comprehensive examination of the drug control policy process in the United States. How are policy choices identified, debated and selected? How are the consequences of governmental policy measured and evaluated? How, if at all, do we learn from our mistakes? Zimring and Hawkins present different ways of understanding American drug policy and provide a foundation for an improved policy process. They argue that protection of children and youth should shape policy toward illicit crime, with attention to the fact that youth protection objectives may limit the effectiveness of some drug controls.

Physician Assistant's Drug Handbook

ISBN: , SKU: , AUTHOR: Springhouse Publishing, PUBLISHER: Springhouse Corporation, This complete guide gives full prescribing data for more than generic and brand name drugs. Includes unlabeled drug uses, highlighted dosage adjustment information, italicized interacting agents, adverse reactions categorized five ways for safety, and a four-way index for quick look-up -- by generic name, trade name, drug class, or disease. Alphabetically organized drug monographs cover generic and trade names; pharmocologic and therapeutic classifications; controlled substance schedule (where appropriate); pregnancy risk category; dosage form; indications, route, and dosage; pharmacodynamics; pharmacokinetics; contraindications and precautions; interactions; effects on diagnostic tests; adverse reactions; overdose and treatment; and special considerations, including patient education and specific instructions for pediatric, geriatric, and breast-feeding patients. Contents include clinical reviewers and consultants, foreword, how to use this book, pharmacology overview, pediatric and geriatric drug therapy, effective prescribing practices, generic drug entries in alphabetical order, a full-color photoguide to more than 320 pills, pharmacologic classes, prescribing authority by state, selected analgesic combination products, topical drugs, immunization schedule, therapeutic drug monitoring guidelines, therapeutic management guidelines, creatinine clearance calculations, pharmaceutical companies listing (drug information contact numbers and Web sites).

Mystic Glyphs: An Oracle Based on Native American Symbols

ISBN: , SKU: , AUTHOR: Rogers, Barb, PUBLISHER: Red Wheel/Weiser, A new and intuitive divination system based on Native American petroglyph symbols in a popular card format, this unique system will appeal to those interested in tarot, runes, medicine cards, Earth-based religions, and Native American spirituality.

Computer Techniques in Preclinical and Clinical Drug

ISBN: , SKU: , AUTHOR: Jackson, Robert C. / Jackson, PUBLISHER: Informa Healthcare, It is estimated that 80 to 90% of drugs under development never make it to the marketplace due to insufficient clinical activity, unacceptable toxicity, rapid appearance of drug resistance, or other factors that should be, at least partially, predictable from preclinical testing. This new text asks the question, How can we use computational methods to improve the success rate in drug development? Computer Techniques in Preclinical and Clinical Drug Development shows how modeling makes it possible to extract the maximum amount of information and predictive value from preclinical data. Computer modeling methods from the areas of pharmacokinetics, pharmacodynamics, cytokinetics, and inhibition kinetics of multi-enzyme pathways are all discussed in this unique reference source.

American Drug Index : Published by Facts and Comparisons

ISBN: , SKU: , AUTHOR: Billups, Norman F. / Billups, Shirley M. / Facts & Comparisons, PUBLISHER: Lippincott Williams & Wilkins, Rigorously updated for , ADI contains more than entries and retains its reputation as the most complete and current listing of drugs and drug products available in a single source. Practical features include: alphabetically listed drug names, extensive cross-indexing phonetic pronunciations, and complete information on the distributor's brand name, composition and strength, pharmaceutical forms available, package size, use, common abbreviations, and a listing of orphan drugs. The electronic version contains an audio pronunciation feature and color photographs of more than 900 pills.

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