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Computer Techniques in Preclinical and Clinical Drug

ISBN: , SKU: , AUTHOR: Jackson, Robert C. / Jackson, PUBLISHER: Informa Healthcare, It is estimated that 80 to 90% of drugs under development never make it to the marketplace due to insufficient clinical activity, unacceptable toxicity, rapid appearance of drug resistance, or other factors that should be, at least partially, predictable from preclinical testing. This new text asks the question, How can we use computational methods to improve the success rate in drug development? Computer Techniques in Preclinical and Clinical Drug Development shows how modeling makes it possible to extract the maximum amount of information and predictive value from preclinical data. Computer modeling methods from the areas of pharmacokinetics, pharmacodynamics, cytokinetics, and inhibition kinetics of multi-enzyme pathways are all discussed in this unique reference source.

Cookin' with Coolio: 5 Star Meals at a 1 Star Price

ISBN: , SKU: , AUTHOR: Coolio, PUBLISHER: Atria Books, THERE'S ONLY ONE THING THAT COOLIO'S BEEN DOING LONGER THAN RAPPING: COOKING Coolio started making thirty-minute meals when he was ten years old and has since developed a whole new cuisine: Ghetto Gourmet. His recipes are built around solid comfort foods with a "healthy twist" that don't break the bank. Start your Ghetto Gourmet adventure with some "Soul Rolls," follow-up with "Finger-Lickin', Rib-Stickin', Fall-Off-the-Bone-and-into-Your-Mouth Chicken," and fi nish off with "Banana Ba-ba-ba-bread" sweetened with golden honey. Chapters such as "How to Become a Kitchen Pimp," "Chillin' and Grillin'," and "Pasta Like a Rasta" will guide you through creating 5 star meals at a 1 star price. You can't fi nd fusions like Blasian (black Asian) or Ghettalian (ghetto Italian) in restaurants, but you can have them cooking away in your kitchen faster and easier than ordering takeout. As Coolio says, "All you need is a little bit of food, and a little bit of know-how."

The Frugal Gardener: How to Have More Garden for Less Money

ISBN: , SKU: , AUTHOR: Erler, Catriona Tudor / Tudor Erler, Catriona, PUBLISHER: Rodale Press, With warmth, wit, and detail, garden guru Catriona Tudor Erler teaches you which tools you need for essential garden jobs, how to help hoses find the "fountain of youth", whether to repair, replace or rent equipment, and hundreds more thrifty lessons. "What Will You Save?" and "25 Smart Shopping Tips" sidebars put frugal facts right at readers' green thumbs. Whether you are planting a perennial border or pumpkin patch, this resource will help you spend little and grow a lot

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The Not-Yet-Employed College Graduate Survival Guide: How to

ISBN: , SKU: , AUTHOR: Snyder, Bonnie Kerrigan, PUBLISHER: Adams Media Corporation, Real-life advice for getting through the economic downturn. You've spent hundreds of hours searching and applying for jobs in your field, but you still haven't landed anything. What gives? Unfortunately, in today's market, it doesn't really matter how impressive your resume is or how well you interview--there simply aren't enough jobs for everyone. "The Not-Yet-Employed College Graduate Survival Guide" isn't just another career handbook. Inside, you'll find honest, real-life advice and strategies for dealing with the downturn in the job market. Since it'll be some time before the current economic climate changes, this book shows you how to switch your focus toward your immediate needs--such as paying off student loans and making rent each month--in order to alleviate the debt you've accumulated while in school. You'll also learn how to position yourself as a standout candidate when jobs arise with valuable exercises that sharpen your interview skills, professional online presence, and resume. With "The Not-Yet-Employed College Graduate Survival Guide," you won't have to give up on your dream career to make ends meet today.

Genders 24: On Your Left: The New Historical Materialism

ISBN: , SKU: , AUTHOR: Kibbey, Ann / Werblowsky, R. J. Zwi / Siegel, Carol, PUBLISHER: New York University Press, In these spirited and powerfully written essays, a new generation of intellectuals makes its mark, challenging conservatives and liberals alike to chart a new course for a responsible politics in contemporary society. A new intellectual movement on the left emerges here. No longer trapped by the old polarizing antagonism between Marxism and feminism, these authors demonstrate as never before the need for an awaremess of gender as it affects every aspect of our society. At the same time, these paradigmatic essays map out a new terrain for feminist thinking, one that fully recognizes the complex workings of gender and leaves oppositional feminism far behind. In the keynote essay, Ambivalence as Alibi, Rosemary Hennessy challenges the most basic assumptions of postmodern sophistication to forge a compelling sytheseis of political, economic, and artistic theory. Betty Joseph, Jennifer Brody, and Poonam Pillai break through the shibboleths of Western liberal tolerance to describe gender inequalities that are intrinsically inter-cultural. Eileen Cleere demonstrates that novels are an important source for understanding how people interpret the economic conditions in which they live, linking social history and literary criticism in a provocative new way. Bridget Elliott uncovers the unusual social and artistic imagination of Marie Laurencin, an artist who was both working-class and avant-garde, and who makes us rethink basic assumptions of artistic form in the visual representation of women. Laura Lyons, analyzing the no-wash protest among IRA prisoners, discovers a new kind of political protest that draws on performance art and the discourse of the body for its political symbolism. And Joseph Litvak, in a highly suggestive critical reading, makes us wonder if the New Historicism may possibly owe its greatest debt to the charming young men of Jane Austen's fictitious world. > go to the Genders website] Acquista Ora

Fundamental Principles of Engineering Nanometrology

ISBN: , SKU: , AUTHOR: Leach, Richard K., PUBLISHER: William Andrew Publishing, "Fundamental Principles of Engineering Nanometrology" provides a comprehensive overview of engineering metrology and how it relates to micro and nanotechnology (MNT) research and manufacturing. By combining established knowledge with the latest advances from the field, it presents a comprehensive single volume that can be used for professional reference and academic study. Provides a basic introduction to measurement and instruments Thoroughly presents numerous measurement techniques, from static length and displacement to surface topography, mass and force Covers multiple optical surface measuring instruments and related topics (interferometry, triangulation, confocal, variable focus, and scattering instruments) Explains, in depth, the calibration of surface topography measuring instruments (traceability; calibration of profile and areal surface texture measuring instruments; uncertainties) Discusses the material in a way that is comprehensible to even those with only a limited mathematical knowledge

Co-Creating a Public Philosophy for Future Generations

ISBN: , SKU: , AUTHOR: Kim, Tae-Chang / Dator, James / Dator, James A., PUBLISHER: Praeger, When making decisions, governments can and should strive consciously to balance the demands of the present with the needs of future generations. Various advocates for greater governmental foresight have created new processes or institutions within existing systems of democratic government. These include long-range planning departments, futures commissions, requirements for future-impact statements on proposed legislation, environmental protection agencies, and offices of technology assessment. But, as the contributors to this volume demonstrate, much more remains to be done. Some of the provocative questions posed by this book include: What is a public philosophy oriented to the needs of future generations necessary, and why is it necessary? What are the major examples of actual experiments in future-oriented governance? What were their successes and failures, and the reasons for each? And finally, what are the obstacles to future-oriented governance, and how might they be overcome? The authors of the essays in this volume suggest answers based on their extensive experience in working with governments, trying to help them incorporate techniques of foresight into their institutions and practices.

Anti-Hacker Tool Kit [With CDROM]

ISBN: , SKU: , AUTHOR: Shema, Mike / Davis, Chris / Philipp, Aaron, PUBLISHER: McGraw-Hill/Osborne Media, "Stop hackers in their tracks" Organized by category, "Anti-Hacker Tool Kit, Third Edition" provides complete details on the latest and most critical security tools, explains their function, and demonstrates how to configure them to get the best results. Completely revised to include the latest security tools, including wireless tools New tips on how to configure the recent tools on Linux, Windows, and Mac OSX New on the CD-ROM -- Gnoppix, a complete Linux system, ClamAV anti-virus, Cain, a multi-function hacking tool, Bluetooth tools, protocol scanners, forensic tools, and more New case studies in each chapter

Cereal Tycoon: Henry Parsons Crowell: Founder of the Quaker

ISBN: , SKU: , AUTHOR: Musser, Joe, PUBLISHER: Moody Publishers, A story of a man who, in his business lunches with great leaders, his work to rid the city of Chicago of debauchery, or his contributions to the Moody Bible Institute, above all sought to share Christ with those around him. See how the vows Crowell made as a young man came to fruition.

Mix Smart: Pro Audio Tips for Your Multitrack Mix

ISBN: , SKU: , AUTHOR: Case, Alex, PUBLISHER: Focal Press, After you've recorded the perfect song, you're only halfway there Mixing is where the magic really happens and getting the perfect mix is a challenge. One of the most illusive arts of the recording practice, mixing can take a lifetime to master - this handbook jump-starts your skills and fast-forwards your progress Breaking the mix down by different effects - EQ, distortion, compression, expansion, pitch shift, delay, reverb, and more - and applying them to some of the most important instruments in pop music, "Mix Smart" will arm you with the skills and techniques you need to tap into your musicality and express it through multitrack mixing, putting true professional quality mixing within your reach. *Future proof, ear-opening strategies will empower your inner-musician, giving you the knowledge you need to develop your mixing skills - from basic to advanced *Breaking the mix down by different effects, with detailed strategies for the most important pop instruments showing you how to create the perfect combination *Bonus Website packed with samples and example tracks, so you can practice as you learn *"Mix Smart" Quick Start summaries at the end of each chapter get you to work faster *Demystifies the technical, making the tools of the mix rig accessible - analog and digital, outboard and in the box, stereo and surround *For everyone who mixes - studio, live, music, film, games, and broadcast The recording studio is your musical instrument, and it's time you really learned how to play. Alex Case shows you not just how to mix well, but how to "Mix Smart" *Future proof, ear-opening strategies to empower your inner-musician, not a list of cookbook recipes. *The Mix is broken down effect by effect (EQ, compression, expansion, delay, pitch shift, reverb), with strategies detailed for the most important pop instruments (vocals, drums, bass, guitar, keys) *Website includes samples and example tracks, illustrating mixing concepts Acquista Ora

Teach Them Spanish!: Grade K

ISBN: , SKU: , AUTHOR: Waltzer-Hackett, Winnie, PUBLISHER: Instructional Fair, Teach Them Spanish is for the teacher who has a little knowledge of Spanish and a lot of enthusiasm. This book guides you through practical lessons in beginning Spanish. Students with little or no previous Spanish will experience the thrill of success with a second language. Lessons appropriate for kindergarten are organized by topics familiar to the student, such as colors, clothing, food, family, and animals. Each lesson includes a simple-to-follow teacher lesson plan, a practice page, and activity pages. Lessons also include games, puzzles, songs, chants, and writing activities. Try this fun and practical program for teaching and learning basic Spanish.

The Gift of Fear: Survival Signals That Protect Us from

ISBN: , SKU: , AUTHOR: de Becker, Gavin, PUBLISHER: Dell Publishing Company, True fear is a gift. Unwarranted fear is a curse. Learn how to tell the difference. A date won't take "no" for an answer. The new nanny gives a mother an uneasy feeling. A stranger in a deserted parking lot offers unsolicited help. The threat of violence surrounds us every day. But we "can" protect ourselves, by learning to trust--and act on--our gut instincts. In this empowering book, Gavin de Becker, the man Oprah Winfrey calls the nation's leading expert on violent behavior, shows you how to spot even subtle signs of danger--before it's too late. Shattering the myth that most violent acts are unpredictable, de Becker, whose clients include top Hollywood stars and government agencies, offers specific ways to protect yourself and those you love, including...how to act when approached by a stranger...when you should fear someone close to you...what to do if you are being stalked...how to uncover the source of anonymous threats or phone calls...the biggest mistake you can make with a threatening person...and more. Learn to spot the danger signals others miss. It might just save your life. "From the Paperback edition."

Exploring Materials: Creative Design for Everyday Objects

ISBN: , SKU: , AUTHOR: Alesina, Inna / Lupton, Ellen, PUBLISHER: Princeton Architectural Press, Materials are like words. The richer your design vocabulary, the more distinctive the design solutions you can express. Sketching ideas with a pencil or rendering them with computer software are useful experiences, but there is no substitute for confronting physical forms and materials directly. Exploring Materials is an action-oriented, accessible guide to design thinking that addresses both the 'how' and 'why' of product design. In place of the abstraction of pure forms or the whimsy of virtual objects, it encourages designers to make and test real objects in a studio environment. Best-selling author Ellen Lupton (Thinking with Type) and her colleague Inna Alesina examine materials from several points of view, including traditional uses, experimental uses, techniques and directions for prototyping with everyday objects, and environmental implications. Student exercises and inspiring examples from the world of contemporary product design show readers how to use materials as tools for thinking and making. The book opens with two extensive studies: one for a place for sitting and one for a method for carrying. By considering what is needed instead of what specific product can be made, designers examine the methodology of designing. The core of the book is a visual glossary of thirty-two materials from corrugated cardboard to molded felt to plastic film. It highlights the materials' behaviors and properties which suggest different types of structure, surface, and connection and it shows experimental uses of these materials, demonstrating how designers from around the world have exploited their characteristics in inventive ways. The book concludes with a section on making it real, moving beyond the prototype to create a product that can be manufactured and marketed. Exploring Materials contains everything designers need not only to jump-start their design process, but also to follow a project through from idea to prototype to finished object.

Breakthrough International Negotiation: How Great

ISBN: , SKU: , AUTHOR: Watkins, Michael / Peres, Shimon / Rosegrant, Susan, PUBLISHER: Jossey-Bass, This fascinating and instructive book offers a revealing, blow-by-blow description of secret, headline-making negotiations in the Middleast, Korea, Africa, and Bosnia, as well as an invaluable guide to conducting such a difficult process of tremendous practical application to a wide variety of conflict resolution professionals. Based on extensive interviews and research with key players at the highest level, this book not only tells some incredibly dramatic stories but shows how to use these demonstrated strategies, skills, improvisational interventions and other techniques. Detailing breakthrough negotiations which brought the Israelis and Palestinians together for the first time in Oslo, built the Gulf War Coalition, ended the great divide between North and South Korea, and terminated the war in Bosnia, the authors employ a compelling narrative and didactic style to explain how to understand and apply sophisticated, field-tested methods of dispute resolution in a variety of situations. Acquista Ora

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Accelerated Silverlight 3

ISBN: , SKU: , AUTHOR: Ghoda, Ashish / Scanlon, Jeff, PUBLISHER: Apress, Accelerated Silverlight 3 teaches you how to get up to speed with the latest version of Silverlight quickly and efficiently. The book assumes you're already comfortable with the basics of.NET coding and with WPF and builds on your existing knowledge to make your journey to Silverlight 3 proficiency as quick and painless as possible. Where coding techniques are similar to other, more established, areas of.NET, the text says so. Likewise, where there's a syntax or conceptual "gotcha" that you're existing coding habits will walk you into, the text points that out, too. This book provides you with fast-track coverage of all the most important elements of the Silverlight 3 technology ranging from XAML to standard controls, from dealing with media to networking, from testing to deployment. It concludes with a pair of fully worked sample applications for you to follow through, because nothing reinforces your understanding of how concepts fit together as much as looking at finished code. It is assumed that readers are already be comfortable with the workings of the.NET Framework. Knowledge of Expression Blend is useful, but not mandatory: you'll learn the Blend techniques that you need to know as you go through the book. By the end, you will have followed a sound, concise, path to mastery of Silverlight 3. What you'll learn Migrate your existing.NET skills to Silverlight 3 as quickly as possible Learn everything you need to know to start developing quality Silverlight 3 applications with confidence Explore worked case studies showing techniques and best practices in a code-heavy style that you can relate to Who is this book for? This book is for.NET developers, whether they are previewing.NET 4.0, already using.NET 3.5, or are in the process of migrating up from.NET 2.0. The aim is to ease people's migration paths as much as possible, so the text includes notes to highlight important features of.NET 3.5 and 4.0 that people need to be aware of and also to highlight where Silverlight's working and syntax differs substantially from that of WPF. About the Apress Accelerated Series The fastest path to mastery, with a rapid tutorial covering best industry practices and a permanent reference you'll keep by your desk.

Basic Documents Supplement to International Law, Cases and

ISBN: , SKU: , AUTHOR: NA, PUBLISHER: West, NA Acquista Ora

Surrender: The Heart God Controls

ISBN: , SKU: , AUTHOR: DeMoss, Nancy Leigh / Cymbala, Jim, PUBLISHER: Moody Publishers, All to Jesus I surrender. I surrender all.' The famous hymn of the faith describes the exact starting point for becoming a true disciple of Christ: total surrender of self. Nancy Leigh DeMoss knows that God desires a heart willing to unconditionally surrender everything to Him. In this new book, Nancy encourages readers to lay it all down before the King, making the difficult, yet rewarding choice to become a slave of Jesus Christ, in a never-ending loving relationship with Him.

How to Manage Your Money

ISBN: , SKU: , AUTHOR: Burkett, Larry, PUBLISHER: Moody Publishers, Designed to get you on track toward a liberated financial life. A step-by-step, in-depth study of God's principles for money management. For groups or individuals.

Prison to Praise

ISBN: , SKU: , AUTHOR: Carothers, Merlin R., PUBLISHER: Merlin R. Carothers, "A most inspired account of the grace of God working in a human life..." Norman Vincent Peale An enlightening book that is not about a prison with bars, but about a prison of circumstances - and how to be set free Millions say it has changed their lives and introduced them to the solution to their problems.

How to Make Your First Million Investing in Real Estate

ISBN: , SKU: , AUTHOR: John Wilson, PUBLISHER: iUniverse Inc, NA

The Power of Transformation How to Find Physical, Spiritual

ISBN: , SKU: , AUTHOR: Pauline E Lewinson, PUBLISHER: iUniverse com, NA

When Love Meets Fear: How to Become Defense-Less and

ISBN: , SKU: , AUTHOR: David Richo, PUBLISHER: Paulist Press, NA

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