Peptide-Based Drug Design
ISBN: , SKU: , AUTHOR: Otvos Jr, Laszlo / Otvos, Laszlo, PUBLISHER: Humana Press, Due to ong>theong>ir high specificity and low toxicity profile, peptides have once again become central to ong>theong> development of new drugs. In Peptide-Based Drug ong>Designong>: Methods and Protocols, expert researchers provide a handbook which offers a selection of research and production tools suitable for transforming a promising protein fragment or stand-alone native peptide ong>intoong> a pharmaceutically acceptable composition. ong>Theong> volume delves ong>intoong> contemporary, cutting-edge subjects such as hit isolation and target validation, computer-aided ong>designong>, sequence modifications to satisfy pharmacologists, in vivo stability and imaging, and ong>theong> actual production of difficult sequences. Written in ong>theong> highly successful Methods in Molecular Biologya" series format, chapters include readily reproducible, step-by-step laboratory protocols, lists of materials, and ong>theong> Notes section, which highlights ong>tipsong> on troubleshooting and avoiding known pitfalls. Comprehensive and up-to-date, Peptide-Based Drug ong>Designong>: Methods and Protocols shows its subject to be an independent science on ong>theong> rise, and provides scientists with a clear, concise guide for continuing this vital research. Acquista Ora