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Western Civilizations: Their History & Their Culture

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Cross-Over Trials in Clinical Research

ISBN: , SKU: , AUTHOR: Senn, S. J. / Senn, Stephen, PUBLISHER: John Wiley & Sons, Statistics in Practice A new series of practical books outlining the use of statistical techniques in a wide range of application areas: Human and Biological SciencesEarth and Environmental SciencesIndustry, Commerce and FinanceCross-over Trials in Clinical Research Stephen Senn Biometrics, Medical Department, CIBA-Geigy Ltd, Basle, Switzerland Cross-over Trials in Clinical Research provides a practical introduction to this important tool within the pharmaceutical industry. Aimed at guiding practitioners in the methods of using cross-over designs efficiently, this book presents a fresh insight into how such trials may be designed and analysed. Key features of this comprehensive treatment are: A focus on the two-period AB/BA design, including the most up-to-date developments in this topic.Important aspects of special design-- graphical and tabular presentation of trials, robust approaches to analysis, and practical issues in planning.Direct relevance to drug development with an approach rooted firmly in biology and pharmacokinetics rather than stressing the mathematical aspects.All techniques included are discussed and illustrated in detail with many practical examples drawn from the author' s wide-ranging experience.This book will prove an invaluable reference to all statisticians and researchers in the pharmaceutical industry. It will also appeal to physicians involved in clinical research. Acquista Ora

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MS Excel Data Analysis and Business Modelling

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Quantitative PCR Protocols

ISBN: , SKU: , AUTHOR: Kochanowski, Bernd / Reischl, Udo, PUBLISHER: Humana Press, This is a significant collection of established and novel methods for the successful quantitation of nucleic acids. Each method has been refined and tested by its developer and proven to work in such problems as the analysis of eukaryotic gene expression, the quantitation of viral loads in clinical specimens, reporter gene expression, and quantitative oncogene analysis. Particular emphasis is placed on the underlying principles of the design of competitive or noncompetitive standards, as well as on the optimization of the amplification process. In important cases several methods are given for the same problem so that readers may set up test systems tailored to their specific practical needs. With its step-by-step instructions, Quantitative PCR Protocols allows researchers to address biological and diagnostic questions that are difficult or impossible to answer using any other experimental approach.

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