Tissue Engineering, Stem Cells and Gene Therapies
ISBN: , SKU: , AUTHOR: Elcin, Y. Murat / Elc'in, Y. Murat / Elgin, Y. Murat, PUBLISHER: Springer, In recent years cell-based technologies have gained significant scientific attention, and have become a matter ong>ofong> intense public debate as well. Namely, (i) tissue engineering, ong>theong> construction ong>ofong> tissues and whole organs using molecularly-designed resorbable biomaterials to create new tissue de novo with or without transplanting cells; (ii) ong>theong> potential use ong>ofong> human embryonic stem cells for transplantation and regenerative medicine (with similar potential for adult-derived stem cells); (iii) and gene ong>theong>rapy, in relation with cell transplantation, have taken ong>theong>ir places as ong>theong> most discussed biomedical issues ong>ofong> ong>theong> day. New findings in biomimetic materials, cell signalling pathways, extracellular matrix receptors and ligands, growth factors, and ong>theong> human genome project are motivating ong>theong> developments in ong>theong>se challenging research areas. This book includes manuscripts on tissue engineering, stem cells and gene ong>theong>rapies authored by world-renowned scientists ong>ofong> ong>theong> field. ong>Theong> first section ong>ofong> ong>theong> volume consists ong>ofong> four chapters giving perspectives for ong>theong> current status and potential future ong>ofong> tissue engineering and stem cell technologies. ong>Theong> second section ong>ofong> ong>theong> volume includes five chapters based on experimental and clinical data. In this section, ong>theong> role ong>ofong> stem cells in liver tissue engineering, cell-based ong>theong>rapies in diabetes mellitus, and chronic degenerative diseases ong>ofong> ong>theong> central nervous system, and adult-derived stem cell ong>theong>rapies are discussed. ong>Theong> two chapters ong>ofong> ong>theong> third section focus on ong>theong> biomarkers for tissue-engineered products, namely for tissue-engineered skin. ong>Theong> eight chapters ong>ofong> ong>theong> fourth section discuss novel biomaterials developed for neural-, vascular-, aortic-, bone-, cartilage- and endocrine pancreas-tissue engineering applications. ong>Theong> last section ong>ofong> ong>theong> book includes chapters on practical gene targeting applications, controlled release in gene ong>theong>rapy and tissue engineering, antibodies in cancer, acute-phase genes and phage-displayed peptide libraries. ong>Proceedingsong> ong>ofong> BIOMED a" ong>Theong> 9th International ong>Symposiumong> on Biomedical Science and Technology, held September , in Antalya, Turkey.