Peptide-Based Drug Design
ISBN: , SKU: , AUTHOR: Otvos Jr, Laszlo / Otvos, Laszlo, PUBLISHER: Humong>anong>a Press, Due to their high specificity ong>anong>d low toxicity profile, peptides have once again become central to the development of new drugs. In Peptide-ong>Basedong> Drug Design: Methods ong>anong>d Protocols, expert researchers provide a hong>anong>dbook which offers a selection of research ong>anong>d production tools suitable for trong>anong>sforming a promising protein fragment or stong>anong>d-alone native peptide into a pharmaceutically acceptable composition. The volume delves into contemporary, cutting-edge subjects such as hit isolation ong>anong>d target validation, computer-aided design, sequence modifications to satisfy pharmacologists, in vivo stability ong>anong>d imaging, ong>anong>d the actual production of difficult sequences. Written in the highly successful Methods in Molecular Biologya" series format, chapters include readily reproducible, step-by-step laboratory protocols, lists of materials, ong>anong>d the Notes section, which highlights tips on troubleshooting ong>anong>d avoiding known pitfalls. Comprehensive ong>anong>d up-to-date, Peptide-ong>Basedong> Drug Design: Methods ong>anong>d Protocols shows its subject to be ong>anong> independent science on the rise, ong>anong>d provides scientists with a clear, concise guide for continuing this vital research. Acquista Ora